DNA origami nanoneedles on freestanding lipid membranes as a tool to observe isotropic-nematic transition in two dimensions.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25467421.
- Also identified by DOI 10.1021/nl504158h.
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Abstract
We introduce a simple experimental system to study dynamics of needle-like nanoobjects in two dimensions (2D) as a function of their surface density close to the isotropic-nematic transition. Using fluorescence correlation spectroscopy, we find that translational and rotational diffusion of rigid DNA origami nanoneedles bound to freestanding lipid membranes is strongly suppressed upon an increase in the surface particle density. Our experimental observations show a good agreement with results of Monte Carlo simulations of Brownian hard needles in 2D.
Medical subject headings
- DNA
- Lipid Bilayers
- Models, Chemical
- Nanostructures