Purloined mechanisms of bacterial immunity can cure muscular dystrophy.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25470540.
- Also identified by DOI 10.1016/j.cmet.2014.11.011 and PMC identifier 4467519.
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Abstract
Myriad strategies have been explored to compensate for the lack of dystrophin or to skip mutations that cause the lethal disease Duchenne muscular dystrophy (DMD). A new study shows that gene editing strategies used by bacteria can be applied in zygotes of a mouse model of DMD to correct the genetic defect that causes muscular dystrophy (Long et al., 2014).
Medical subject headings
- Bacteria
- Dystrophin
- Muscular Dystrophy, Duchenne