Resolving lipids: lipoxins regulate reverse cholesterol transport.
Level V
Where this comes from
- Record sourced from PubMed, PMID 25470544.
- Also identified by DOI 10.1016/j.cmet.2014.11.012.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Disruptions in cholesterol homeostasis contribute to cardiovascular disease (CVD). In a recent issue of Cell Metabolism, Demetz et al. (2014) report that endogenous lipoxygenase-mediated metabolism of another lipid, arachidonic acid, produces lipoxins that regulate reverse cholesterol transport. These results suggest that lipoxins may represent a novel class of therapeutics for CVD.
Medical subject headings
- Arachidonic Acid
- Cholesterol
- Metabolome