Bugs and food: a recipe for cancer?
Level V
Where this comes from
- Record sourced from PubMed, PMID 25470545.
- Also identified by DOI 10.1016/j.cmet.2014.11.010 and PMC identifier 4364408.
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Abstract
Obesity and the associated state of subchronic inflammation are risk factors for numerous pathologies, including carcinogenesis. Recently, Schulz et al. (2014) demonstrated that high-fat diet-induced intestinal dysbiosis promotes cancer development in K-ras(G12Dint) mice without inducing obesity or mucosal inflammation, positioning microbial activities as a central component of diet-induced carcinogenesis.
Medical subject headings
- Carcinogenesis
- Diet, High-Fat
- Dietary Fats
- Dysbiosis
- Intestinal Neoplasms
- Obesity