Short sleep duration increases the risk of chronic kidney disease in shift workers.

Abstract

To investigate the association of sleep duration and shift work with development of chronic kidney disease (CKD) in Japanese workers. A total of 3600 participants without CKD were observed for an average of 4.4 years. The Cox proportional-hazards regression model was used to estimate hazard ratios and 95% confidence intervals of the risk of CKD associated with sleep duration and shift work. Sleep duration and shift work showed no significant association with the risk of CKD. Nevertheless, when the results were stratified by shift work status, short sleep duration was associated with a significantly higher risk of CKD among shift workers (hazard ratio = 3.60; 95% confidence interval: 1.52 to 10.68). Short sleep duration was a risk factor for early CKD but only among shift workers.