Stem cell RNA epigenetics: m(6)arking your territory.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 25479740.
- Also identified by DOI 10.1016/j.stem.2014.11.011.
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Abstract
Modifications of mRNAs can have a profound effect on cellular function and differentiation. In this issue of Cell Stem Cell, Batista et al. (2014) describe fundamental parameters of N(6)-methyl-adenosine modification of mRNAs in embryonic stem cells and provide strong evidence that modification plays a role in exit from pluripotency toward differentiation.
Medical subject headings
- Adenine
- Embryonic Stem Cells
- Homeodomain Proteins
- Methyltransferases