Patching up broken hearts: cardiac cell therapy gets a bioengineered boost.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25479741.
- Also identified by DOI 10.1016/j.stem.2014.11.008 and PMC identifier 7153519.
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Abstract
Preclinical and clinical studies for cardiac cell therapy have only seen moderate success due to poor engraftment and survival of transplanted cells. In this issue of Cell Stem Cell, Ye et al. (2014) employ a growth-factor-loaded fibrin patch and show improved cardiovascular cell survival after cell transplantation into a porcine model of ischemia reperfusion.
Medical subject headings
- Endothelial Cells
- Heart Ventricles
- Induced Pluripotent Stem Cells
- Myocardial Infarction
- Myocardium
- Myocytes, Cardiac
- Myocytes, Smooth Muscle
- Stem Cell Transplantation