The nucleolus gets the silent treatment.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 25479743.
- Also identified by DOI 10.1016/j.stem.2014.11.017 and PMC identifier 5533169.
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Abstract
In this issue of Cell Stem Cell, Savić et al. (2014) and Kim et al. (2014) provide insight into how global heterochromatin condensation and LIN28 sequestration in embryonic stem cells are independent mechanisms regulating pluripotency in the oft-overlooked nucleolus.
Medical subject headings
- Cell Nucleolus
- Chromosomal Proteins, Non-Histone
- Embryonic Stem Cells
- Genes, rRNA
- MicroRNAs
- Neurons
- Pluripotent Stem Cells
- RNA, Long Noncoding
- RNA-Binding Proteins