On-chip cavity-enhanced absorption spectroscopy using a white light-emitting diode and polymer mirrors.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25494304.
- Also identified by DOI 10.1039/c4lc01264j.
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Abstract
We have developed a disposable microfluidic chip with integrated cavity mirrors comprised of two pieces of 3M Vikuiti™ enhanced specular reflector II (ESRII) film, for performing cavity-enhanced absorption spectroscopy with a white light-emitting diode (LED). Compared to measurements made with a chip without cavity mirrors, the absorption path length is enhanced by a maximum factor of 28 at 544 nm, and the sensitivity is enhanced by approximately 5 times, enabling micromolar range detection limits to be achieved in an optical path length of only 50 μm.
Medical subject headings
- Light
- Polymers
- Spectrum Analysis