Right superior temporal gyrus volume in adolescents with a history of suicide attempt.

Pan, Lisa A; Ramos, Lisa; Segreti, AnnaMaria; Brent, David A; Phillips, Mary L · Br J Psychiatry · 2015

cross_sectional · Level IV

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Abstract

The extent to which observed differences in emotion processing and regulation neural circuitry in adolescents with a history of suicide attempt are paralleled by structural differences is unknown. We measured brain cortical thickness and grey- and white-matter volumes in 100 adolescents: 28 with a history of suicide attempt and major depressive disorder (MDD); 31 with a history of MDD but no suicide attempt; and a healthy control group (n = 41). The first group compared with controls showed reduction in grey-matter volume in the right superior temporal gyrus (BA38), a region important for social emotion processing.

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