Immune escape mechanisms as a guide for cancer immunotherapy.

Beatty, Gregory L; Gladney, Whitney L · Clin Cancer Res · 2015

review · Level V

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Abstract

Immunotherapy has demonstrated impressive outcomes for some patients with cancer. However, selecting patients who are most likely to respond to immunotherapy remains a clinical challenge. Here, we discuss immune escape mechanisms exploited by cancer and present strategies for applying this knowledge to improving the efficacy of cancer immunotherapy.

Medical subject headings