Nanostructured microfluidic digestion system for rapid high-performance proteolysis.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25511010.
- Also identified by DOI 10.1039/c4lc01165a and PMC identifier 4304898.
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Abstract
A novel microfluidic protein digestion system with a nanostructured and bioactive inner surface was constructed by an easy biomimetic self-assembly strategy for rapid and effective proteolysis in 2 minutes, which is faster than the conventional overnight digestion methods. It is expected that this work would contribute to rapid online digestion in future high-throughput proteomics.
Medical subject headings
- Lab-On-A-Chip Devices
- Nanostructures
- Proteolysis