Pluripotent-stem-cell-derived epicardial cells: a step toward artificial cardiac tissue.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25517459.
- Also identified by DOI 10.1016/j.stem.2014.10.007.
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Abstract
Epicardial cells are crucial for heart development, function, and regeneration, but methods to study them have been lacking. Using WNT and BMP signaling pathways, Witty et al. (2014) have now developed an elaborate method to generate fully functional epicardial cells from human pluripotent stem cells, allowing their in vitro investigation.
Medical subject headings
- Cell Lineage
- Pericardium
- Pluripotent Stem Cells