Stem cells to insulin secreting cells: two steps forward and now a time to pause?
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25517460.
- Also identified by DOI 10.1016/j.stem.2014.10.012.
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Abstract
Two groups recently reported the in vitro differentiation of human embryonic stem cells into insulin-secreting cells, achieving an elusive goal for regenerative medicine. Herein we provide a perspective regarding these developments, compare phenotypes of the insulin-containing cells to human β cells, and discuss implications for type 1 diabetes research and clinical care.
Medical subject headings
- Insulin-Secreting Cells
- Stem Cells