ESC-derived retinal pigmented epithelial cell transplants in patients: so far, so good.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25517461.
- Also identified by DOI 10.1016/j.stem.2014.10.008.
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Abstract
Many untreatable blinding diseases involve degeneration of retinal pigmented epithelial (RPE) cells, which has prompted exploration of the therapeutic potential of human-pluripotent-stem-cell-derived RPE. The first safety trials reported in The Lancet of embryonic-stem-cell-derived RPE cell transplants indicate no serious adverse outcomes and encourage further investigation.
Medical subject headings
- Embryonic Stem Cells
- Retinal Pigment Epithelium
- Stem Cell Transplantation