A recombinant avian leukosis virus subgroup j for directly monitoring viral infection and the selection of neutralizing antibodies.
basic_science · Level V
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- Record sourced from PubMed, PMID 25522008.
- Also identified by DOI 10.1371/journal.pone.0115422 and PMC identifier PMC254409.
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Abstract
Avian leukosis virus subgroup J (ALV-J) has induced serious clinical outbreaks and has become a serious infectious disease of chickens in China. We describe here the creation of a recombinant ALV-J tagged with the enhanced green fluorescent protein (named rHPRS-103EGFP). We successfully utilize the rHPRS-103EGFP to visualize viral infection and for development of a simplified serum-neutralization test.