Acetate fuels the cancer engine.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 25525870.
- Also identified by DOI 10.1016/j.cell.2014.12.009.
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Abstract
Cancer cells have distinctive nutrient demands to fuel growth and proliferation, including the disproportionate use of glucose, glutamine, and fatty acids. Comerford et al. and Mashimo et al. now demonstrate that several types of cancer are avid consumers of acetate, which facilitates macromolecular biosynthesis and histone modification.