Lab on a chip for continuous-flow magnetic cell separation.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 25537573.
- Also identified by DOI 10.1039/c4lc01422g.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Separation of cells is a key application area of lab-on-a-chip (LOC) devices. Among the various methods, magnetic separation of cells utilizing microfluidic devices offers the merits of biocompatibility, efficiency, and simplicity. This review discusses the fundamental physics involved in using magnetic force to separate particles, and identifies the optimisation parameters and corresponding methods for increasing the magnetic force. The paper then elaborates the design considerations of LOC devices for continuous-flow magnetic cell separation. Examples from the recently published literature illustrate these state-of-the-art techniques.
Medical subject headings
- Cell Separation
- Lab-On-A-Chip Devices
- Magnetic Phenomena