No effect of proton pump inhibitors on crying and irritability in infants: systematic review of randomized controlled trials.
systematic_review · Level I
Where this comes from
- Record sourced from PubMed, PMID 25556017.
- Also identified by DOI 10.1016/j.jpeds.2014.11.030.
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Abstract
Proton pump inhibitors are increasingly being used to treat infants with crying and/or irritability based on the assumption that these symptoms are attributable to gastroesophageal reflux. However, the data from a systematic review of randomized controlled trials do not support the use of proton pump inhibitors to decrease infant crying and irritability.
Medical subject headings
- Crying
- Emotions
- Gastroesophageal Reflux
- Irritable Mood
- Proton Pump Inhibitors
- Randomized Controlled Trials as Topic