Osteoimmunology in 2014: Two-faced immunology-from osteogenesis to bone resorption.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 25561367.
- Also identified by DOI 10.1038/nrrheum.2014.219.
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Abstract
Even though activation of immunity is associated with bone destruction, new mechanisms have been described in 2014 through which immunology-associated pathways can cooperate to support osteogenesis. These advances support the view of the immune system as a central mechanism which can regulate bone homeostasis, regeneration and destruction.
Medical subject headings
- Bone Resorption
- Osteogenesis
- Scleroderma, Systemic