rbamtools: an R interface to samtools enabling fast accumulative tabulation of splicing events over multiple RNA-seq samples.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 25563331.
- Also identified by DOI 10.1093/bioinformatics/btu846.
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Abstract
The open source environment R isf the most widely used software to statistically explore biological data sets including sequence alignments. BAM is the de facto standard file format for sequence alignment. With rbamtools, we provide now a full spectrum of accessibility to BAM for R users such as reading, writing, extraction of subsets and plotting of alignment depth where the script syntax closely follows the SAM/BAM format. Additionally, rbamtools enables fast accumulative tabulation of splicing events over multiple BAM files.
Medical subject headings
- Algorithms
- Computational Biology
- High-Throughput Nucleotide Sequencing
- RNA Splicing
- Sequence Alignment
- Sequence Analysis, RNA
- Software