Dysfunctional families: Clostridium scindens and secondary bile acids inhibit the growth of Clostridium difficile.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 25565200.
- Also identified by DOI 10.1016/j.cmet.2014.12.016 and PMC identifier 6333312.
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Abstract
C. difficile infection is a deadly disease that is influenced by the microbiome. In a recent article in Nature, Buffie et al. (2014) demonstrate that the ability of C. scindens to synthesize secondary bile acids is crucial to providing resistance to C. difficile infection.
Medical subject headings
- Bile Acids and Salts
- Clostridioides difficile
- Disease Susceptibility
- Intestinal Mucosa
- Intestines
- Microbiota