NRG4: an endocrine link between brown adipose tissue and liver.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 25565202.
- Also identified by DOI 10.1016/j.cmet.2014.12.008.
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Abstract
Brown adipose tissue (BAT) directly regulates energy homeostasis via uncoupling of mitochondrial ATP production and thermogenesis. Wang et al. (2014) now report that BAT controls liver lipogenesis via secretion of the growth factor NRG4.
Medical subject headings
- Adipose Tissue, Brown
- Lipogenesis
- Liver
- Neuregulins
- Obesity
- RNA, Messenger
- Receptor, ErbB-3
- Receptor, ErbB-4