Radiofrequency ablation of drug-resistant cancer cells using molecularly targeted carboxyl-functionalized biodegradable graphene.

Sasidharan, Abhilash; Sivaram, Amal J; Retnakumari, Archana P; Chandran, Parwathy; Malarvizhi, Giridharan Loghanathan; Nair, Shantikumar; Koyakutty, Manzoor · Adv Healthc Mater · 2015

basic_science · Level V

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Abstract

Under ultralow radiofrequency (RF) power, transferrin-conjugated graphene nanoparticles can thermally ablate drug- or radiation-resistant cancer cells very effectively. The results suggest that graphene-based RF hyperthermia can be an efficient method to manage drug-/radiation-resistant cancers.

Medical subject headings