One step creation of multifunctional 3D architectured hydrogels inducing bone regeneration.

Neffe, Axel T; Pierce, Benjamin F; Tronci, Giuseppe; Ma, Nan; Pittermann, Erik; Gebauer, Tim; Frank, Oliver; Schossig, Michael et al. · Adv Mater · 2015

basic_science · Level V

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Abstract

Structured hydrogels showing form stability and elastic properties individually tailorable on different length scales are accessible in a one-step process. They support cell adhesion and differentiation and display growing pore size during degradation. In vivo experiments demonstrate their efficacy in biomaterial-induced bone regeneration, not requiring addition of cells or growth factors.

Medical subject headings