Tolerance of benznidazole in a United States Chagas Disease clinic.

Miller, David A; Hernandez, Salvador; Rodriguez De Armas, Lissette; Eells, Samantha J; Traina, Mahmoud M; Miller, Loren G; Meymandi, Sheba K · Clin Infect Dis · 2015

prospective_cohort · Level II

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Abstract

The US-based Center of Excellence for Chagas Disease performed an observational study on the safety and tolerance of benznidazole 5 mg/kg/day for 60 days in 30 adults with chronic Chagas disease. The side-effect profile was suboptimal, including 5 cases of debilitating neuropathy and an unusually high angioedema rate.

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