I spy alloreactive T cells.
Level V
Where this comes from
- Record sourced from PubMed, PMID 25632032.
- Also identified by DOI 10.1126/scitranslmed.aaa5083.
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Abstract
High-throughput sequencing of the T cell receptor Vβ CDR3 region allowed longitudinal tracking of alloreactive T cells in kidney transplant patients, revealing clonal deletion as a mechanism of transplantation tolerance (Morris et al., this issue).
Medical subject headings
- Clonal Deletion
- Kidney Failure, Chronic
- Kidney Transplantation
- Receptors, Antigen, T-Cell
- T-Lymphocytes
- Transplantation Tolerance