Hexamodal imaging with porphyrin-phospholipid-coated upconversion nanoparticles.

Rieffel, James; Chen, Feng; Kim, Jeesu; Chen, Guanying; Shao, Wei; Shao, Shuai; Chitgupi, Upendra; Hernandez, Reinier et al. · Adv Mater · 2015

basic_science · Level V

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Abstract

Hexamodal imaging using simple nanoparticles is demonstrated. Porphyrin-phospholipids are used to coat upconversion nanoparticles in order to generate a new biocompatible material. The nanoparticles are characterized in vitro and in vivo for imaging via fluorescence, upconversion, positron emission tomography, computed tomography, Cerenkov luminescence, and photoacoustic tomography.

Medical subject headings