Progression of renal damage in glycogen storage disease type I is associated to hyperlipidemia: a multicenter prospective Italian study.
prospective_cohort · Level II
Where this comes from
- Record sourced from PubMed, PMID 25641239.
- Also identified by DOI 10.1016/j.jpeds.2014.12.015.
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Abstract
Angiotensin converting enzyme (ACE)-inhibitors decrease glomerular hyperfiltration but not microalbuminuria and proteinuria in glycogen storage disease type I. In the current study, we demonstrated that severe hyperlipidemia is associated with ACE-inhibitor ineffectiveness. We underline the importance of adequate metabolic control in glycogen storage disease type I. A combination therapy with ACE-inhibitors and lipid lowering drugs might be considered.
Medical subject headings
- Angiotensin-Converting Enzyme Inhibitors
- Forecasting
- Glycogen Storage Disease Type I
- Hyperlipidemias
- Hypolipidemic Agents
- Kidney Diseases
- Lipids