Interleukin-18 is associated with protection against rhinovirus-induced colds and asthma exacerbations.
prospective_cohort · Level II
Where this comes from
- Record sourced from PubMed, PMID 25645216.
- Also identified by DOI 10.1093/cid/civ062.
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Abstract
Rhinoviruses cause the common cold and exacerbations of asthma. Animal models of infection have identified a protective role for interleukin-18 (IL-18). Following experimental rhinovirus infection, we observed increased respiratory symptoms in healthy and asthmatic subjects with low nasal and bronchial IL-18 levels.
Medical subject headings
- Asthma
- Common Cold
- Interleukin-18
- Rhinovirus