Can circulating tumor cells predict resistance in metastatic breast cancer?
Where this comes from
- Record sourced from PubMed, PMID 25645864.
- Also identified by DOI 10.1158/1078-0432.CCR-14-2967 and PMC identifier 4694574.
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Abstract
Circulating tumor cell (CTC) enumeration provides prognostic but not predictive information for chemotherapy in metastatic breast cancer. Because CTC measurement is reproducible and allows molecular profiling, an assay to assess endocrine resistance was developed. Whether this CTC-based assay can be used to reliably select endocrine therapy must be tested.
Medical subject headings
- Breast Neoplasms
- Ki-67 Antigen
- Neoplastic Cells, Circulating
- Proto-Oncogene Proteins c-bcl-2
- Erb-b2 Receptor Tyrosine Kinases
- Receptors, Estrogen