Functional mapping of the human visual cortex with intravoxel incoherent motion MRI.
Where this comes from
- Record sourced from PubMed, PMID 25647423.
- Also identified by DOI 10.1371/journal.pone.0117706 and PMC identifier 4315413.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Functional imaging with intravoxel incoherent motion (IVIM) magnetic resonance imaging (MRI) is demonstrated. Images were acquired at 3 Tesla using a standard Stejskal-Tanner diffusion-weighted echo-planar imaging sequence with multiple b-values. Cerebro-spinal fluid signal, which is highly incoherent, was suppressed with an inversion recovery preparation pulse. IVIM microvascular perfusion parameters were calculated according to a two-compartment (vascular and non-vascular) diffusion model. The results obtained in 8 healthy human volunteers during visual stimulation are presented. The IVIM blood flow related parameter fD* increased 170% during stimulation in the visual cortex, and 70% in the underlying white matter.
Medical subject headings
- Diffusion Magnetic Resonance Imaging
- Echo-Planar Imaging
- Visual Cortex