Boosting bacterial metabolism to combat antibiotic resistance.
Level V
Where this comes from
- Record sourced from PubMed, PMID 25651168.
- Also identified by DOI 10.1016/j.cmet.2015.01.012.
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Abstract
The metabolic state of a bacterial cell influences its susceptibility to antibiotics. In this issue, Peng et al. (2015) show that resistant bacteria can be sensitized to antibiotic treatment through the addition of exogenous metabolites that stimulate central metabolic pathways and increase drug uptake.
Medical subject headings
- Alanine
- Anti-Bacterial Agents
- Bacteria
- Drug Resistance, Bacterial
- Glucose
- Kanamycin