A new notch for lung stem cells.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 25658364.
- Also identified by DOI 10.1016/j.stem.2015.01.012.
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Abstract
Homeostasis and repair of different lung compartments require the selective activation of specific progenitor/stem cells and their regulated differentiation to yield cell types that fulfill specialized regional functions. In this issue of Cell Stem Cell, Pardo-Saganta et al. (2015) identify Notch signaling as a determinant of basal cell heterogeneity and fate decisions in pseudostratified airways.
Medical subject headings
- Cell Lineage
- Respiratory Mucosa
- Stem Cells
- Wounds and Injuries