Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses.
Level V
Where this comes from
- Record sourced from PubMed, PMID 25672590.
- Also identified by DOI 10.1039/c5lc00055f and PMC identifier 4375736.
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Abstract
Rapid point-of-care (POC) diagnostic devices are needed for field-forward screening of severe acute systemic febrile illnesses. Multiplexed rapid lateral flow diagnostics have the potential to distinguish among multiple pathogens, thereby facilitating diagnosis and improving patient care. Here, we present a platform for multiplexed pathogen detection using multi-colored silver nanoplates. This design requires no external excitation source and permits multiplexed analysis in a single channel, facilitating integration and manufacturing.
Medical subject headings
- Dengue Virus
- Ebolavirus
- Metal Nanoparticles
- Microfluidic Analytical Techniques
- Silver
- Virology
- Yellow fever virus