RNA: jack of all trades and master of all.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25679756.
- Also identified by DOI 10.1016/j.cell.2015.01.047.
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Abstract
Noncoding RNAs have regulatory capabilities that evolution harnesses to fulfill diverse functions. Lee et al. show that a noncoding RNA from Epstein-Barr virus recruits a host transcription factor to silence virus gene expression and propose that it does this through base-pairing with nascent viral transcripts.
Medical subject headings
- Herpesvirus 4, Human
- PAX5 Transcription Factor
- RNA, Viral