Target-specific 3D DNA gatekeepers for biomimetic nanopores.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25683922.
- Also identified by DOI 10.1002/adma.201405078.
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Abstract
3D cross-linked DNA superstructures switch off the ionic flux through solid-state nanopores with extremely high ON-OFF ratios of 10(3) -10(5) . This gating mechanism can be generally applicable in a wide range of nanopores with opening diameters up to 650 nm. The 3D bio-supramolecular gatekeepers outperform previous low-dimensional or simple-structured DNA functional components.
Medical subject headings
- Biomimetic Materials
- DNA
- Nanopores