CCR 20th Anniversary commentary: stayin' alive-antiapoptotic proteins and breast cancer.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 25691771.
- Also identified by DOI 10.1158/1078-0432.CCR-14-2548 and PMC identifier 4333724.
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Abstract
The control of cell death involves a complex interaction of multiple proteins. In a study published in the January 1, 2000, issue of Clinical Cancer Research, Tanaka and colleagues demonstrated that one of the proapoptotic proteins, survivin, was frequently expressed in breast cancer. In the subsequent years, effectors of apoptosis have translated into important prognostic indicators and potential therapeutic targets.
Medical subject headings
- Apoptosis
- Apoptosis Regulatory Proteins
- Breast Neoplasms