Regulation of Cellular Response Pattern to Phosphorus Ion is a New Target for the Design of Tissue-Engineered Blood Vessel.

Chen, Wen; Wang, Fangjuan; Zeng, Wen; Sun, Jun; Li, Li; Yang, Mingcan; Sun, Jiansen; Wu, Yangxiao et al. · Adv Healthc Mater · 2015

basic_science · Level V

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Abstract

Regulation of cellular response pattern to phosphorus ion (PI) is a new target for the design of tissue-engineered materials. Changing cellular response pattern to high PI can maintain monocyte/macrophage survival in TEBV and the signal of increasing PI can be converted by klotho to the adenosine signals through the regulation of energy metabolism in monocytes/macrophages.

Medical subject headings