GlycanAnalysis Plug-in: a database search tool for N-glycan structures using mass spectrometry.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25712693.
- Also identified by DOI 10.1093/bioinformatics/btv110.
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Abstract
UNLABELLED: Tandem mass spectrometry (MS/MS or MS(n)) is a potent technique for characterizing N-glycan structures. GlycanAnalysis searches a glycan database to support the identification of glycan structures from MS/MS spectra. It also calculates diagnostic ions of glycan structures registered in a glycan database (GlycomeDB or KEGG GLYCAN) and searches for MS/MS spectra of N-glycans that match diagnostic ions to determine the structures. This program functions as a plug-in for Mass++, a freeware mass spectrum visualization and analysis program. AVAILABILITY AND IMPLEMENTATION: The executable files of Mass++ are available for free at http://www.first-ms3d.jp/english/. The GlycanAnalysis plug-in is included in the standard package of Mass++ for Windows. CONTACT: k-morimt@shimadzu.co.jp or nishikaz@shimadzu.co.jp or acyshzw@shimadzu.co.jp SUPPLEMENTARY INFORMATION: Supplementary material are available at Bioinformatics online.
Medical subject headings
- Databases, Factual
- Glycopeptides
- Polysaccharides
- Search Engine
- Software
- Tandem Mass Spectrometry