Anesthetic neurotoxicity--clinical implications of animal models.

Rappaport, Bob A; Suresh, Santhanam; Hertz, Sharon; Evers, Alex S; Orser, Beverley A · N Engl J Med · 2015

basic_science · Level V

Where this comes from

Abstract

Some anesthetics and sedatives have been shown to cause neurotoxic effects in laboratory animals. The FDA collaboration SmartTots recommends undertaking large-scale clinical studies and avoiding nonurgent surgical procedures requiring anesthesia in children younger than 3 years of age.

Medical subject headings