Experimental stem cell therapies on burn wound: do source, dose, timing and method matter?
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25716759.
- Also identified by DOI 10.1016/j.burns.2015.01.005.
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Abstract
Stem cell therapy has been introduced as a new and promising modality of wound covering in recent decade. It has been used for improvement of burn wound, post burn scar and saving stasis zone of burn with good results. However, there have been some differences between the various experimental burn wound trials in stem cell source, therapeutic dose, delivery method and timing of stem cell delivery. In our study, we aimed to review stem cell biology and investigate discrepancies in animal trials of use of stem cells in burn wound account for the variation in, stem cell source, therapeutic dose, delivery method and timing of stem cell delivery.
Medical subject headings
- Burns
- Embryonic Stem Cells
- Mesenchymal Stem Cell Transplantation
- Wound Healing