FFAR out new targets for diabetes.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 25738452.
- Also identified by DOI 10.1016/j.cmet.2015.02.015.
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Abstract
Dyslipidemia has long been associated with β cell dysfunction in the development of diabetes. Tang et al. (2015) have now revealed that β cell short-chain fatty acid receptors FFA2 and FFA3 are activated in an autocrine fashion and reduce insulin secretion in type 2 diabetes models.
Medical subject headings
- Blood Glucose
- Diabetes Mellitus, Type 2
- Insulin
- Insulin-Secreting Cells
- Receptors, G-Protein-Coupled