Synthesis, structural and antioxidant studies of some novel N-ethyl phthalimide esters.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25742494.
- Also identified by DOI 10.1371/journal.pone.0119440 and PMC identifier 4351070.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
A series of N-ethyl phthalimide esters 4(a-n) were synthesized and characterized by spectroscopic studies. Further, the molecular structure of majority of compounds were analysed by single crystal X-ray diffraction studies. The X-ray analysis revealed the importance of substituents on the crystal stability and molecular packing. All the synthesized compounds were tested for in vitro antioxidant activity by DPPH radical scavenging, FRAP and CUPRAC methods. Few of them have shown good antioxidant activity.
Medical subject headings
- Antioxidants
- Esters
- Phthalimides