Generation of electrospun nanofibers with controllable degrees of crimping through a simple, plasticizer-based treatment.

Liu, Wenying; Lipner, Justin; Moran, Christine H; Feng, Liangzhu; Li, Xiyu; Thomopoulos, Stavros; Xia, Younan · Adv Mater · 2015

basic_science · Level V

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Abstract

Electrospun nanofibers with controllable degrees of crimping are fabricated by simply exposing the samples to a plasticizer at preset shrinkage ratios. Compared with their straight counterparts, the crimped nanofibers are able to mechanically mimic native tendon tissue and better protect tendon fibroblasts under uniaxial strains.

Medical subject headings