Proteo-lipobeads for the oriented encapsulation of membrane proteins.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25763882.
- Also identified by DOI 10.1039/c4sm02646b and PMC identifier 4387127.
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Abstract
As a surrogate of live cells, proteo-lipobeads are presented, encapsulating functional membrane proteins in a strict orientation into a lipid bilayer. Assays can be performed just as on live cells, for example using fluorescence measurements. As a proof of concept, we have demonstrated proton transport through cytochrome c oxidase.
Medical subject headings
- Electron Transport Complex IV
- Lipid Bilayers
- Sepharose