Mitosis, diffusible crosslinkers, and the ideal gas law.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25768899.
- Also identified by DOI 10.1016/j.cell.2015.02.048.
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Abstract
During mitosis, molecular motors hydrolyze ATP to generate sliding forces between adjacent microtubules and form the bipolar mitotic spindle. Lansky et al. now show that the diffusible microtubule crosslinker Ase1p can generate sliding forces between adjacent microtubules, and it does so without ATP hydrolysis.
Medical subject headings
- Microtubules