Role of endogenous pain modulation in chronic pain mechanisms and treatment.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 25789433.
- Also identified by DOI 10.1097/01.j.pain.0000460343.46847.58.
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Abstract
Development and application of psychophysical test paradigms to assess endogenous pain modulation in healthy controls and in patients yielded large body of data over the last 2 decades. These tests can assist in predicting pain acquisition, in characterizing pain syndromes and related dysfunctions of pain modulation, and in predicting response to treatment. This chapter reviews the development of thought on pain modulation in the clinical setup, focusing on conditioned pain modulation, and update on accumulated data regarding the mechanism, protocols of administration, and applications in the clinic.
Medical subject headings
- Central Nervous System Sensitization
- Chronic Pain
- Conditioning, Psychological