Easy to use plastic optical fiber-based biosensor for detection of butanal.

Cennamo, Nunzio; Di Giovanni, Stefano; Varriale, Antonio; Staiano, Maria; Di Pietrantonio, Fabio; Notargiacomo, Andrea; Zeni, Luigi; D'Auria, Sabato · PLoS One · 2015

Level V

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Abstract

The final goal of this work is to achieve a selective detection of butanal by the realization of a simple, small-size and low cost experimental approach. To this end, a porcine odorant-binding protein was used in connection with surface plasmon resonance transduction in a plastic optical fiber tool for the selective detection of butanal by a competitive assay. This allows to reduce the cost and the size of the sensing device and it offers the possibility to design a "Lab-on-a-chip" platform. The obtained results showed that this system approach is able to selectively detect the presence of butanal in the concentration range from 20 μM to 1000 μM.

Medical subject headings