Airborne Exposure of Methyl Methacrylate During Simulated Total Hip Arthroplasty and Fabrication of Antibiotic Beads.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 25795235.
- Also identified by DOI 10.1016/j.arth.2015.02.036.
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Abstract
As the use of cement remains prevalent in orthopedic surgery, so do concerns over the safety of its active ingredient, methyl methacrylate (MMA). The Occupational Health and Safety Agency (OSHA) limits the airborne exposure to 100 parts per million (ppm) averaged over an 8 hour period. We measured MMA exposure to operating room personnel during simulated total hip arthroplasty (THA), antibiotic bead fabrication and simulated spill of MMA. Cumulative and peak exposures during simulated THA and antibiotic bead fabrication did not exceed OSHA limits of 100ppm. Vacuum mixing and greater distance from the vapor source reduced measured MMA exposure. Spilled MMA led to prolonged and elevated MMA levels. MMA levels returned to a negligible level in all scenarios by 20 minutes after mixing.
Medical subject headings
- Air Pollutants, Occupational
- Bone Cements
- Environmental Monitoring
- Inhalation Exposure
- Occupational Exposure
- Polymethyl Methacrylate
Anatomy
- hip